| Venue: Kings Park Stadium. |
| Final started at 16:10 | time | | bib | | 1. Marie Josee Ta Lou | CIV | 22.81s | Oq | 366 | | 2. Alyssa Conley | RSA | 22.84s | Oq | 5 | | 3. Gina Bass | GAM | 22.92s | Oq | 503 | | 4. Justine Palframan | RSA | 23.22s | | 26 | | 5. Janet Amponsah | GHA | 23.45s | | 522 | | 6. Udaya Ada | LBR | 23.67s | | 808 | | 7. Loungo Matihaku | BOT | 24.18s | | 293 | | -. Nazie Adeline Gouenon | CIV | DNS | | 360 |
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| Entry Standard 24.0s/24.24s to be obtained from January 1, 2015 to May 23, 2016. | | Olympic Standard 23.20s to be obtained from January 1, 2015 to July 11, 2016. |
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| Semi 1 started at 16:10 Wind +0.8m/s | time | | bib | | 1. Alyssa Conley | RSA | 23.02s | Oq | 5 | | 2. Gina Bass | GAM | 23.31s | | 503 | | 3. Gaha Parfaite | CIV | 24.23s | | 803 | | 4. Aurelie Alcindor | MRI | 24.23s | | 677 | | 5. Rhoda Njobvu | ZAM | 24.50s | | 188 | | -. Flings Owusu-Agyapong | GHA | DNS | | 535 | | -. Millicent Ndoro | KEN | DNS | | 575 | | -. Ontiretse Molapisi | BOT | DNS | | 294 |
| Semi 2 Wind +1.0m/s | time | | bib | | 1. Marie Josee Ta Lou | CIV | 22.89s | Oq | 366 | | 2. Janet Amponsah | GHA | 23.54s | | 522 | | 3. Loungo Matihaku | BOT | 23.80s | | 293 | | 4. Marcelle Cecilia Bouele Bondo | CGO | 23.99s | | 335 | | 5. Assia Raziki | MAR | 24.31s | | 633 | | 6. Tegest Tamangu Yuma | ETH | 24.45s | | 472 | | 7. Joanilla Janvier | MRI | 24.83s | | 681 | | -. Tamzin Thomas | RSA | DNS | | 38 |
| Semi 3 Wind +1.0m/s | time | | bib | | 1. Justine Palframan | RSA | 23.37 | | 26 | | 2. Udaya Ada | LBR | 23.80 | | 808 | | 3. Nazie Adeline Gouenon | CIV | 23.96 | | 360 | | 4. Eunice Kadogo | KEN | 24.04 | | 572 | | 5. Josephine Anokye | GHA | 24.31 | | 523 | | 6. Germaine Abessolo Bivina | CMR | 24.42 | | 376 | | -. Natacha Ngoye Akamabi | CGO | DNF | | 340 | | -. Phumlile Ndzinisa | SWZ | DNF | | 145 |
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| Heat 1 started at 09:30 Wind +0.7m/s | time | | bib | | 1. Justine Palframan | RSA | 23.45s | | 26 | | 2. Loungo Matihaku | BOT | 23.99s | | 293 | | 3. Aurelie Alcindor | MRI | 24.42s | | 677 | | 4. Natacha Ngoye Akamabi | CGO | 24.54s | | 340 | | 5. Hafsathu Kamara | SLE | 24.99s | | 120 | | 6. Sukoluhle Mlalazi | ZIM | 26.13s | | 203 | | -. Murielle Ahoure | CIV | DNS | | 357 |
| Heat 2 Wind +0.6m/s | time | | bib | | 1. Alyssa Conley | RSA | 23.52s | | 5 | | 2. Phumlile Ndzinisa | SWZ | 23.67s | | 145 | | 3. Marcelle Cecilia Bouele Bondo | CGO | 24.04s | | 335 | | 4. Nazie Adeline Gouenon | CIV | 24.23s | | 360 | | 5. Josephine Anokye | GHA | 24.51s | | 523 | | 6. Joanilla Janvier | MRI | 24.81s | | 681 | | 7. Viola Lado | SSD | 26.98s | | 773 | | -. Amal Mohamed Bashir | SOM | DNS | | 122 |
| Heat 3 Wind +0.4m/s | time | | bib | | 1. Janet Amponsah | GHA | 23.76s | | 522 | | 2. Tamzin Thomas | RSA | 23.92s | | 38 | | 3. Gaha Parfaite | CIV | 24.11s | | 803 | | 4. Tegest Tamangu Yuma | ETH | 24.23s | | 472 | | 5. Rhoda Njobvu | ZAM | 24.35s | | 188 | | 6. Mary Chepkoech | KEN | 25.05s | | 814 | | 7. Mildred Priscilla Gamba | UGA | 25.43s | | 178 |
| Heat 4 Wind -0.4m/s | time | | bib | | 1. Marie Josee Ta Lou | CIV | 23.22s | | 366 | | 2. Udaya Ada | LBR | 23.75s | | 808 | | 3. Assia Raziki | MAR | 24.51s | | 633 | | 4. Millicent Ndoro | KEN | 24.75s | | 575 | | 5. Ontiretse Molapisi | BOT | 24.96s | | 294 | | 6. Tsitsi Mahachi | ZIM | 25.38s | | 199 | | 7. Prenam Pesse | TOG | 25.62s | | 159 |
| Heat 5 Wind +1.4m/s | time | | bib | | 1. Gina Bass | GAM | 23.14s | Oq | 503 | | 2. Eunice Kadogo | KEN | 24.05s | | 572 | | 3. Flings Owusu-Agyapong | GHA | 24.23s | | 535 | | 4. Germaine Abessolo Bivina | CMR | 24.73s | | 376 | | 5. Eveline Sanches | CPV | 25.73s | | 404 | | 6. Yvonne Thomas | ZIM | 25.89s | | 205 | | 7. Margret Hassan | SSD | 27.61s | | 772 | | 8. Rachel Zenzo | COD | 28.25s | | 795 |
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