| Final 17:00 | | time | gap | L | Butter | Back | Breast | | 1. Catherine van Rensburg |  South Africa | 4:56.13 | | 6 | 1:08.18 | 2:25.51 | 3:48.32 | | 2. Hamida Rania Nefsi |  Algeria | 5:01.60 | +5.47s | 4 | 1:08.72 | 2:27.16 | 3:50.51 | | 3. Kate Jill Meyer | South Africa | 5:02.63 | +6.50s | 5 | 1:07.69 | 2:27.10 | 3:51.19 | | 4. Nadine Abdallah |  Egypt | 5:05.29 | +9.16s | 3 | 1:09.06 | 2:27.59 | 3:55.52 | | 5. Jasmine Eissa | Egypt | 5:12.92 | +16.79s | 2 | 1:08.31 | 2:31.66 | 4:00.13 | | 6. Molina Smalley |  Namibia | 5:15.81 | +19.68s | 7 | 1:09.77 | 2:34.05 | 4:02.45 | | 7. Jihane Benchadu | Algeria | 6:21.27 | +25.14s | 1 | 1:09.15 | 2:30.16 | 4:02.00 |
| World Record: Samantha McIntosh, Canada 4:25.87 Toronto, Canada 1st April 2023 | | African Record: Kirsty Coventry, Zimbabwe 4:29.89 OG Beijing, China 10th August 2008 | | Championship Record: Kirsty Coventry, Zimbabwe 4:39.91 Alger, Algeria 7th July 2007 |
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